
NanoTalks
- Miguel Ángel Esteve & Cristianne Rijcken
- 28/04/2026
Active Targeting in LNPs: Why Surface Functionalization Matters
Explore how active targeting strategies define the specificity, efficiency, and translational potential of lipid nanoparticle-based therapies.
This article examines how key factors such as surface functionalization, ligand conjugation strategies, and shielding lipid design directly impact targeting performance, cellular uptake, and biological outcomes. It also explores how advanced conjugation technologies, such as CliCr®, enable controlled and scalable functionalization of LNPs, supporting the development of targeted nanoparticle systems from early research to GMP-ready processes.
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- Miguel Ángel Esteve
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