--- title: Nanotalks, Curapath blog description: Explore Curapath's blog dive into PNP and LNP formulations, GMP manufacturing, and solutions for non-viral gene therapy, all this in Nanotalks by Curapath image: https://blog.curapath.com/hubfs/Captura%20de%20pantalla%202025-03-10%20102446.png --- [Skip to content](https://blog.curapath.com/all#main-content) [![White](https://blog.curapath.com/hs-fs/hubfs/White.png?width=553&height=208&name=White.png "White")](https://curapath.com/) - [Resources](https://resources.curapath.com/en/curapath-resource-library) - [End to end services](https://curapath.com/end-to-end-services/) - [Expertise](https://curapath.com/expertise/) - [Products](https://curapath.com/products) - [Blog](https://blog.curapath.com) - [Contact Us](https://curapath.com/contact-us/)  ![](https://blog.curapath.com/hs-fs/hubfs/logo%20Nanotalks%20blog%20Curapath%20banco-png.png?width=6000&height=3375&name=logo%20Nanotalks%20blog%20Curapath%20banco-png.png) NanoTalks by Curapath is your gateway to the future of healthcare nanotechnology. In each episode, we explore the latest trends in lipid and polymer nanoparticles a groundbreaking field transforming how next-generation therapies and vaccines are developed. Discover how these tiny, multifunctional structures can enhance treatment effectiveness, minimize side effects, and open the door to innovations that once seemed out of reach. Join us as we delve into cutting-edge research, clinical insights, and the major advances shaping modern medicine Hot topics # NanoTalks - FEATURED BLOG - Miguel Ángel Esteve - 15/10/2026 ## Polyaminoacids in drug delivery  **Explore how polyamino acids can be tailored to solve key challenges in drug delivery** This article looks at the properties that make polyamino acids versatile materials for therapeutic delivery, from their tunable chemistry to their potential for biodegradable and biocompatible systems. Discover how they can support different delivery strategies, including drug conjugates and nanoparticle platforms, and why their design flexibility makes them promising for next-generation therapies.  [READ ARTICLE](https://blog.curapath.com/lnps-or-pnps-that-is-the-question) ![fotos blog paaa](https://blog.curapath.com/hs-fs/hubfs/fotos%20blog%20paaa.png?width=1920&height=1080&name=fotos%20blog%20paaa.png) Keep exploring Curapath Blog , there is more NanoTalks yet to explore ## Recent Articles - Filter by: - [All](https://blog.curapath.com/all) - [Polymers](https://blog.curapath.com/tag/polymers) - [LNP](https://blog.curapath.com/tag/lnp) - [Regulatory](https://blog.curapath.com/tag/regulatory) - [Analytics](https://blog.curapath.com/tag/analytics) - [PNP](https://blog.curapath.com/tag/pnp) [![](https://blog.curapath.com/hubfs/fotos%20blog%20paaa.png)](https://blog.curapath.com/polyaminoacids-in-drug-delivery) [Polymers](https://blog.curapath.com/tag/polymers), [LNP](https://blog.curapath.com/tag/lnp), [PNP](https://blog.curapath.com/tag/pnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - October 14, 2026 ### [Polyaminoacids in drug delivery](https://blog.curapath.com/polyaminoacids-in-drug-delivery) From biodegradable carriers to stimuli-responsive and multifunctional nanomedicines, poly(amino acids) are opening new... [Read more](https://blog.curapath.com/polyaminoacids-in-drug-delivery) [![](https://blog.curapath.com/hubfs/pnp%20vs%20LNP.png)](https://blog.curapath.com/lnps-or-pnps-that-is-the-question) [Polymers](https://blog.curapath.com/tag/polymers), [LNP](https://blog.curapath.com/tag/lnp), [PNP](https://blog.curapath.com/tag/pnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - September 8, 2026 ### [LNPs or PNPs that is the question](https://blog.curapath.com/lnps-or-pnps-that-is-the-question) Lipid nanoparticles (LNPs) and polymeric nanoparticles (PNPs) are two leading non-viral drug delivery platforms. While... [Read more](https://blog.curapath.com/lnps-or-pnps-that-is-the-question) [![](https://blog.curapath.com/hubfs/fotos%20blog%20july.png)](https://blog.curapath.com/selecting-the-right-polymer-excipient-for-drug-delivery) [Polymers](https://blog.curapath.com/tag/polymers), [Regulatory](https://blog.curapath.com/tag/regulatory) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - July 30, 2026 ### [Selecting the Right Polymer Excipient for Drug Delivery](https://blog.curapath.com/selecting-the-right-polymer-excipient-for-drug-delivery) Historically polymer excipients have been described as inactive formulation components. In today's drug delivery... [Read more](https://blog.curapath.com/selecting-the-right-polymer-excipient-for-drug-delivery) [![](https://blog.curapath.com/hubfs/fotos%20blog%20(10).png)](https://blog.curapath.com/when-does-a-polymer-need-to-be-gmp-grade) [Polymers](https://blog.curapath.com/tag/polymers), [Regulatory](https://blog.curapath.com/tag/regulatory) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - June 25, 2026 ### [When Does a Polymer Need to Be GMP Grade?](https://blog.curapath.com/when-does-a-polymer-need-to-be-gmp-grade) Polymers play a wide variety of rolesin today´s pharmaceutical landscape. They are used as excipients, drug delivery... [Read more](https://blog.curapath.com/when-does-a-polymer-need-to-be-gmp-grade) [![](https://blog.curapath.com/hubfs/fotos%20blog%20(4)-1.jpg)](https://blog.curapath.com/polymers-for-drug-conjugation) [Polymers](https://blog.curapath.com/tag/polymers) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - May 26, 2026 ### [Polymers for Drug Conjugation: From PEGylation to Next-Generation Polymer Therapeutics](https://blog.curapath.com/polymers-for-drug-conjugation) In polymer–drug conjugates, the polymer is not only a passive carrier. Its chemistry, molecular weight, architecture,... [Read more](https://blog.curapath.com/polymers-for-drug-conjugation) [![Targeted LNPs](https://blog.curapath.com/hubfs/fotos%20blog%20(5).png)](https://blog.curapath.com/active-targeting-in-lnps-why-surface-functionalization-matters) [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - April 28, 2026 ### [Active Targeting in LNPs: Why Surface Functionalization Matters](https://blog.curapath.com/active-targeting-in-lnps-why-surface-functionalization-matters) Active targeting has emerged as one of the most promising strategies to unlock extrahepatic delivery of nanoparticles,... [Read more](https://blog.curapath.com/active-targeting-in-lnps-why-surface-functionalization-matters) [![LNP manufacturing](https://blog.curapath.com/hubfs/fotos%20blog%20(3).png)](https://blog.curapath.com/lnp-manufacturing-process) [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - April 2, 2026 ### [LNP Manufacturing Process: From Formulation to GMP Production](https://blog.curapath.com/lnp-manufacturing-process) The outcome of this step directly defines critical quality attributes, including: Particle size Polydispersity index... [Read more](https://blog.curapath.com/lnp-manufacturing-process) [![](https://blog.curapath.com/hubfs/fotos%20blog%20(2).png)](https://blog.curapath.com/advanced-analytical-characterization-of-polymeric-excipients) [Polymers](https://blog.curapath.com/tag/polymers), [LNP](https://blog.curapath.com/tag/lnp), [Analytics](https://blog.curapath.com/tag/analytics) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - February 26, 2026 ### [Advanced Analytical Characterization of Polymeric Excipients](https://blog.curapath.com/advanced-analytical-characterization-of-polymeric-excipients) Polymeric excipients play a critical role in modern therapeutic systems being a fundamental partin advanced and highly... [Read more](https://blog.curapath.com/advanced-analytical-characterization-of-polymeric-excipients) [![](https://blog.curapath.com/hubfs/fotos%20blog%20(1).png)](https://blog.curapath.com/antibacterial-polymers-for-medical-devices) [Polymers](https://blog.curapath.com/tag/polymers) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - January 29, 2026 ### [Antibacterial polymers for medical devices](https://blog.curapath.com/antibacterial-polymers-for-medical-devices) Medical device–associated infections remain a major challenge across healthcare, especially for catheters, orthopedic... [Read more](https://blog.curapath.com/antibacterial-polymers-for-medical-devices) [![](https://blog.curapath.com/hubfs/fotos%20blog%20(1).jpg)](https://blog.curapath.com/polymer-drug-conjugates-explained) [Polymers](https://blog.curapath.com/tag/polymers) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - December 18, 2025 ### [Polymer-Drug Conjugates Explained](https://blog.curapath.com/polymer-drug-conjugates-explained) Polymer–drug conjugates (PDCs) represents a unique strategy in modern drug delivery: instead of encapsulating a drug... [Read more](https://blog.curapath.com/polymer-drug-conjugates-explained) [![](https://blog.curapath.com/hubfs/fotos%20blog.jpg)](https://blog.curapath.com/beyond-lipids-and-polymers-understanding-hybrid-nanoparticles) [Polymers](https://blog.curapath.com/tag/polymers), [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - November 13, 2025 ### [Beyond Lipids and Polymers: Understanding Hybrid Nanoparticles](https://blog.curapath.com/beyond-lipids-and-polymers-understanding-hybrid-nanoparticles) Lipid–polymer hybrid nanoparticles (LPHNs) are emerging as one of the most promising platforms in nanomedicine.... [Read more](https://blog.curapath.com/beyond-lipids-and-polymers-understanding-hybrid-nanoparticles) [![](https://blog.curapath.com/hubfs/Dise%C3%B1o%20sin%20t%C3%ADtulo%20(10).png)](https://blog.curapath.com/the-next-generation-of-transfection-polymers) [Polymers](https://blog.curapath.com/tag/polymers) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - October 15, 2025 ### [The Next Generation of Transfection Polymers](https://blog.curapath.com/the-next-generation-of-transfection-polymers) Transfection, the process of introducing nucleic acids into cells, is a cornerstone of modern biotechnology, enabling... [Read more](https://blog.curapath.com/the-next-generation-of-transfection-polymers) [![](https://blog.curapath.com/hubfs/Dise%C3%B1o%20sin%20t%C3%ADtulo%20(7).png)](https://blog.curapath.com/functionalized-polymers-in-pharmaceutical-therapies) [Polymers](https://blog.curapath.com/tag/polymers) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - September 11, 2025 ### [Functionalized Polymers in Pharmaceutical Therapies](https://blog.curapath.com/functionalized-polymers-in-pharmaceutical-therapies) Functionalized polymers are revolutionizing pharmaceutical science by bridging chemistry and biology in ways that... [Read more](https://blog.curapath.com/functionalized-polymers-in-pharmaceutical-therapies) [![Peg Alternatives page photo](https://blog.curapath.com/hubfs/Dise%C3%B1o%20sin%20t%C3%ADtulo%20(6).png)](https://blog.curapath.com/peg-alternatives) [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - July 30, 2025 ### [PEG Alternatives: Polymers Reshaping Lipid Nanoparticle Drug Delivery](https://blog.curapath.com/peg-alternatives) Replacing PEG in lipid nanoparticles (LNPs) marks a critical evolution in the development of safer and more effective... [Read more](https://blog.curapath.com/peg-alternatives) [![](https://blog.curapath.com/hubfs/Dise%C3%B1o%20sin%20t%C3%ADtulo%20(4).png)](https://blog.curapath.com/polymer-therapeutics) [Polymers](https://blog.curapath.com/tag/polymers) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - July 2, 2025 ### [From Chemistry to Cure: The Rise of Polymer Therapeutics](https://blog.curapath.com/polymer-therapeutics) Over the past 20 years, polymer-based drug delivery systems have evolved from experimental platforms to clinically... [Read more](https://blog.curapath.com/polymer-therapeutics) [![](https://blog.curapath.com/hubfs/Blog.jpg)](https://blog.curapath.com/reimagining-car-t-therapy-in-vivo-engineering-with-lipid-nanoparticles) [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - June 9, 2025 ### [In Vivo CAR-T Therapy with Lipid Nanoparticles: A Non-Viral Approach](https://blog.curapath.com/reimagining-car-t-therapy-in-vivo-engineering-with-lipid-nanoparticles) [Read more](https://blog.curapath.com/reimagining-car-t-therapy-in-vivo-engineering-with-lipid-nanoparticles) [![](https://blog.curapath.com/hubfs/Blog%20%20NANOTALK%20est%C3%A9tica%20banner%20(1).jpg)](https://blog.curapath.com/mrna-vaccines-therapies) [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - May 19, 2025 ### [mRNA Technologies: Vaccines vs Therapeutics](https://blog.curapath.com/mrna-vaccines-therapies) Messenger RNA (mRNA) technology surged into the global spotlight during the COVID-19 pandemic, showcasing its power to... [Read more](https://blog.curapath.com/mrna-vaccines-therapies) [![](https://blog.curapath.com/hubfs/Blog%20%20NANOTALK%20est%C3%A9tica%20banner.jpg)](https://blog.curapath.com/scale-up-in-genetherapy) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - April 29, 2025 ### [From Lab to Plant: Why Scale-Up Is the Key to Success in Biopharma](https://blog.curapath.com/scale-up-in-genetherapy) Early-stage research frequently takes center stage in the fields of biopharmaceuticals and the development of advanced... [Read more](https://blog.curapath.com/scale-up-in-genetherapy) [![](https://blog.curapath.com/hubfs/Blog%20est%C3%A9tica%20banner%20(1).jpg)](https://blog.curapath.com/aseptice-excellence-gene-therapy) - [Elena Gallon](https://blog.curapath.com/author/elena-gallon) - April 8, 2025 ### [Aseptic Excellence in Gene Therapy: Sterile Filtration and Fill & Finish Best Practices](https://blog.curapath.com/aseptice-excellence-gene-therapy) Sterile filtration and aseptic fill & finish are essential components in gene therapy manufacturing, critical for... [Read more](https://blog.curapath.com/aseptice-excellence-gene-therapy) [![](https://blog.curapath.com/hubfs/freepik__the-style-is-candid-image-photography-with-natural__94715.jpeg)](https://blog.curapath.com/active-passive-tageting-nanoparticles) [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - March 20, 2025 ### [The Impact of Passive and Active Targeting in Nanoparticles](https://blog.curapath.com/active-passive-tageting-nanoparticles) Nanoparticle-based drug delivery has revolutionized how therapeutics can be transported and released within the human... [Read more](https://blog.curapath.com/active-passive-tageting-nanoparticles) [![](https://blog.curapath.com/hubfs/blog%20foto.png)](https://blog.curapath.com/process-performance-qualification-ppq-excipients) [Regulatory](https://blog.curapath.com/tag/regulatory) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - March 11, 2025 ### [The Essentials of Process Performance Qualification (PPQ) for Excipients](https://blog.curapath.com/process-performance-qualification-ppq-excipients) Process Performance Qualification (PPQ) is a critical part of the pharmaceutical manufacturing validation lifecycle,... [Read more](https://blog.curapath.com/process-performance-qualification-ppq-excipients) [![](https://blog.curapath.com/hubfs/5.jpg)](https://blog.curapath.com/best-analytical-practices-for-lipid-nanoparticle-formulations) [Analytics](https://blog.curapath.com/tag/analytics) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - March 4, 2025 ### [Optimized Analytical Strategies for Superior Lipid Nanoparticle Formulations](https://blog.curapath.com/best-analytical-practices-for-lipid-nanoparticle-formulations) Currently, lipid nanoparticles (LNPs) stand as the predominant delivery system for emerging mRNA-based therapeutic... [Read more](https://blog.curapath.com/best-analytical-practices-for-lipid-nanoparticle-formulations) [![](https://blog.curapath.com/hubfs/4.jpg)](https://blog.curapath.com/mastering-lnp-formulation-process) [LNP](https://blog.curapath.com/tag/lnp) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - February 10, 2025 ### [From Early stages to GMP: Mastering the LNP Formulation Process](https://blog.curapath.com/mastering-lnp-formulation-process) RNA‑based therapeutics have rapidly evolved from niche research tools to transformative medicines, powering... [Read more](https://blog.curapath.com/mastering-lnp-formulation-process) [![](https://blog.curapath.com/hubfs/1-1.jpg)](https://blog.curapath.com/advancing-peptide-delivery) - [Miguel Ángel Esteve](https://blog.curapath.com/author/miguel-ángel-esteve) - February 10, 2025 ### [Advancing Peptide Delivery: Paving the Way for Next-Generation Therapies](https://blog.curapath.com/advancing-peptide-delivery) Peptide therapeutics offer high specificity and strong safety profiles, but their effectiveness depends on overcoming... [Read more](https://blog.curapath.com/advancing-peptide-delivery) Keep updated ### Sign Up for NanoTalks Subscribe to NanoTalks, the magazine of Curapath. Stay up to date on the latest developments, trends and news in the world of non-viral vectors, plus discover the latest advances in nanobiotechnology.  [![Inverted](https://blog.curapath.com/hs-fs/hubfs/Inverted.png?width=300&height=113&name=Inverted.png "Inverted")](https://curapath.com/) Toggle 1. 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